Efficient gene transfer by a human immunodeficiency virus type 1 (HIV-1)-derived vector utilizing a stable HIV packaging cell line
By transfecting fibroblast cells with an HIV-1-MN molecular clone with a deletion of the major packaging sequence, we have developed a stable HIV-1 packaging cell line, Ψ422. Ψ422 cells form syncytia with CD4-positive cells, correctly express HIV-1 structural proteins, and produce a large amount of...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1996
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19496/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943062/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.24.14070 |
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