Stable human immunodeficiency virus type 1 (HIV-1) resistance in transformed CD4+ monocytic cells treated with multitargeting HIV-1 antisense sequences incorporated into U1 snRNA.

We have approached the development of a human immunodeficiency virus type 1 (HIV-1) therapeutic product by producing immune cells stably resistant to HIV-1. Promonocytic CD4+ cells (U937) were made resistant to HIV-1 by the introduction of a DNA construct (pNDU1A,B,C) that contained three independen...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Liu, D, Donegan, J, Nuovo, G, Mitra, D, Laurence, J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191561/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9094686/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.5.4079-4085.1997
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