The AML1/ETO fusion protein activates transcription of BCL-2

The AML1 gene, located on chromosome 21, is involved in several distinct chromosomal translocations in human leukemia. In t(8;21) acute myelogenous leukemia (AML), the AML1 gene is juxtaposed to the ETO gene located on chromosome 8, generating an AML1/ETO fusion protein. Both AML1/ETO and the AML1 p...

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Detaylı Bibliyografya
Asıl Yazarlar: Klampfer, Lidija, Zhang, Jin, Zelenetz, Andrew O., Uchida, Hideo, Nimer, Stephen D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences of the USA 1996
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC19494/
https://ncbi.nlm.nih.gov/pubmed/8943060
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