E-Cadherin Inhibits Cell Surface Localization of the Pro-Migratory 5T4 Oncofetal Antigen in Mouse Embryonic Stem Cells

Epithelial-mesenchymal transition (EMT) events occur during embryonic development and are important for the metastatic spread of epithelial tumors. We show here that spontaneous differentiation of mouse embryonic stem (ES) cells is associated with an E- to N-cadherin switch, up-regulation of E-cadhe...

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Autori principali: Spencer, Helen L., Eastham, Angela M., Merry, Catherine L.R., Southgate, Thomas D., Perez-Campo, Flor, Soncin, Francesca, Ritson, Sarah, Kemler, Rolf, Stern, Peter L., Ward, Christopher M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949355/
https://ncbi.nlm.nih.gov/pubmed/17507657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-09-0875
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