E-Cadherin Inhibits Cell Surface Localization of the Pro-Migratory 5T4 Oncofetal Antigen in Mouse Embryonic Stem Cells

Epithelial-mesenchymal transition (EMT) events occur during embryonic development and are important for the metastatic spread of epithelial tumors. We show here that spontaneous differentiation of mouse embryonic stem (ES) cells is associated with an E- to N-cadherin switch, up-regulation of E-cadhe...

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Detalhes bibliográficos
Main Authors: Spencer, Helen L., Eastham, Angela M., Merry, Catherine L.R., Southgate, Thomas D., Perez-Campo, Flor, Soncin, Francesca, Ritson, Sarah, Kemler, Rolf, Stern, Peter L., Ward, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949355/
https://ncbi.nlm.nih.gov/pubmed/17507657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-09-0875
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