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c-Myb regulates lineage choice in developing thymocytes via its target gene Gata3

During T-cell development, thymocytes with intermediate avidity for antigen–MHC complexes are positively selected and then differentiate into functional cytotoxic and helper T cells. This process is controlled by signalling from the T-cell receptor (TCR). Here, we show that the c-Myb transcription f...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Maurice, Diane, Hooper, Joel, Lang, Georgina, Weston, Kathleen
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949015/
https://ncbi.nlm.nih.gov/pubmed/17641686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601801
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