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c-Myb regulates the proliferation of immature thymocytes following β-selection

Transgenic mice expressing a T-cell-specific dominant interfering allele (MEnT) of the c-Myb transcription factor have a pronounced block in CD4(–)CD8(–) (DN) development. In this study we show that differentiation of DN MEnT thymocytes is blocked due to the failure of cells to enter the cell cycle...

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Detalhes bibliográficos
Main Authors: Pearson, Richard, Weston, Kathleen
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC305827/
https://ncbi.nlm.nih.gov/pubmed/11080157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.22.6112
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