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Protective Effect of Arginine on Oxidative Stress in Transgenic Sickle Mouse Models

Sickle cell disease (SCD) is characterized by reperfusion injury and chronic oxidative stress. Oxidative stress and hemolysis in SCD result in inactivation of nitric oxide (NO) and depleted arginine levels. We hypothesized that augmenting NO production by arginine supplementation will reduce oxidati...

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Bibliografiske detaljer
Main Authors: Dasgupta, Trisha, Hebbel, Robert P, Kaul, Dhananjay K.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1948977/
https://ncbi.nlm.nih.gov/pubmed/17157180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2006.08.025
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