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Protective Effect of Arginine on Oxidative Stress in Transgenic Sickle Mouse Models
Sickle cell disease (SCD) is characterized by reperfusion injury and chronic oxidative stress. Oxidative stress and hemolysis in SCD result in inactivation of nitric oxide (NO) and depleted arginine levels. We hypothesized that augmenting NO production by arginine supplementation will reduce oxidati...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1948977/ https://ncbi.nlm.nih.gov/pubmed/17157180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2006.08.025 |
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