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Human Acyl-Coenzyme A:Cholesterol Acyltransferase Expressed in Chinese Hamster Ovary Cells: Membrane Topology and Active Site Location

Acyl-CoA:cholesterol acyltransferase (ACAT) is a membrane-bound enzyme that produces cholesteryl esters intracellularly. Two ACAT genes (ACAT1 and ACAT2) have been identified. The expression of ACAT1 is ubiquitous, whereas that of ACAT2 is tissue restricted. Previous research indicates that ACAT1 ma...

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Autori principali: Lin, Song, Lu, Xiaohui, Chang, Catherine C.Y., Chang, Ta-Yuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC194892/
https://ncbi.nlm.nih.gov/pubmed/12808042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-11-0725
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