Human Acyl-Coenzyme A:Cholesterol Acyltransferase Expressed in Chinese Hamster Ovary Cells: Membrane Topology and Active Site Location

Acyl-CoA:cholesterol acyltransferase (ACAT) is a membrane-bound enzyme that produces cholesteryl esters intracellularly. Two ACAT genes (ACAT1 and ACAT2) have been identified. The expression of ACAT1 is ubiquitous, whereas that of ACAT2 is tissue restricted. Previous research indicates that ACAT1 ma...

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Bibliographic Details
Main Authors: Lin, Song, Lu, Xiaohui, Chang, Catherine C.Y., Chang, Ta-Yuan
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2003
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC194892/
https://ncbi.nlm.nih.gov/pubmed/12808042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-11-0725
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