A novel mechanism of action of tetracyclines: Effects on nitric oxide synthases

Tetracyclines have recently been shown to have “chondroprotective” effects in inflammatory arthritides in animal models. Since nitric oxide (NO) is spontaneously released from human cartilage affected by osteoarthritis (OA) or rheumatoid arthritis in quantities sufficient to cause cartilage damage,...

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Detalhes bibliográficos
Main Authors: Amin, Ashok R., Attur, Mukundan G., Thakker, Geeta D., Patel, Prakash D., Vyas, Pranav R., Patel, Rajesh N., Patel, Indravadan R., Abramson, Steven B.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1996
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC19486/
https://ncbi.nlm.nih.gov/pubmed/8943052
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