A novel mechanism of action of tetracyclines: Effects on nitric oxide synthases

Tetracyclines have recently been shown to have “chondroprotective” effects in inflammatory arthritides in animal models. Since nitric oxide (NO) is spontaneously released from human cartilage affected by osteoarthritis (OA) or rheumatoid arthritis in quantities sufficient to cause cartilage damage,...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Amin, Ashok R., Attur, Mukundan G., Thakker, Geeta D., Patel, Prakash D., Vyas, Pranav R., Patel, Rajesh N., Patel, Indravadan R., Abramson, Steven B.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19486/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943052/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.24.14014
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