A novel mechanism of action of tetracyclines: Effects on nitric oxide synthases

Tetracyclines have recently been shown to have “chondroprotective” effects in inflammatory arthritides in animal models. Since nitric oxide (NO) is spontaneously released from human cartilage affected by osteoarthritis (OA) or rheumatoid arthritis in quantities sufficient to cause cartilage damage,...

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Autors principals: Amin, Ashok R., Attur, Mukundan G., Thakker, Geeta D., Patel, Prakash D., Vyas, Pranav R., Patel, Rajesh N., Patel, Indravadan R., Abramson, Steven B.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1996
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC19486/
https://ncbi.nlm.nih.gov/pubmed/8943052
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