A novel mechanism of action of tetracyclines: Effects on nitric oxide synthases

Tetracyclines have recently been shown to have “chondroprotective” effects in inflammatory arthritides in animal models. Since nitric oxide (NO) is spontaneously released from human cartilage affected by osteoarthritis (OA) or rheumatoid arthritis in quantities sufficient to cause cartilage damage,...

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Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Amin, Ashok R., Attur, Mukundan G., Thakker, Geeta D., Patel, Prakash D., Vyas, Pranav R., Patel, Rajesh N., Patel, Indravadan R., Abramson, Steven B.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1996
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19486/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943052/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.24.14014
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