A novel mechanism of action of tetracyclines: Effects on nitric oxide synthases
Tetracyclines have recently been shown to have “chondroprotective” effects in inflammatory arthritides in animal models. Since nitric oxide (NO) is spontaneously released from human cartilage affected by osteoarthritis (OA) or rheumatoid arthritis in quantities sufficient to cause cartilage damage,...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
|---|---|
| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1996
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19486/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943052/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.24.14014 |
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