Kinetics of Oligonucleotide Hybridization to DNA Probe Arrays on High-Capacity Porous Silica Substrates

We have investigated the kinetics of DNA hybridization to oligonucleotide arrays on high-capacity porous silica films that were deposited by two techniques. Films created by spin coating pure colloidal silica suspensions onto a substrate had pores of ∼23 nm, relatively low porosity (35%), and a surf...

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Bibliographic Details
Main Authors: Glazer, Marc I., Fidanza, Jacqueline A., McGall, Glenn H., Trulson, Mark O., Forman, Jonathan E., Frank, Curtis W.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2007
Subjects:
Nucleic Acids
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1948050/
https://ncbi.nlm.nih.gov/pubmed/17496028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.103275
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