Enhanced high density oligonucleotide array-based sequence analysis using modified nucleoside triphosphates.

Pairs of high density oligonucleotide arrays (DNA chips) consisting of >96 000 oligonucleotides were designed to screen the entire 5.53 kb coding region of the hereditary breast and ovarian cancer BRCA1 gene for all possible sequence changes in the homozygous and heterozygous states. Single-stran...

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Autores principales: Hacia, J G, Woski, S A, Fidanza, J, Edgemon, K, Hunt, N, McGall, G, Fodor, S P, Collins, F S
Formato: Artigo
Lenguaje:Inglês
Publicado: 1998
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC147927/
https://ncbi.nlm.nih.gov/pubmed/9776762
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