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TNF-Alpha Represses Transcription of Human Bone Morphogenetic Protein-4 in Lung Epithelial Cells

Bone Morphogenetic Proteins are key signaling molecules in vertebrate development. Little is known about Bmp gene regulation in any organ. In Drosophila, the Bmp gene, dpp is regulated by Dorsal, the invertebrate homologue of Rel-NFkB. In this study we examined whether TNF-alpha, which activates NF-...

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Detalhes bibliográficos
Main Authors: Zhu, Nian-Ling, Li, Changgong, Huang, Hao Hao, Sebald, Matthew, Londhe, Vedang A., Heisterkamp, Nora, Warburton, David, Bellusci, Saverio, Minoo, Parviz
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1945170/
https://ncbi.nlm.nih.gov/pubmed/17350185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2007.01.016
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