Point mutations in segment I-S6 render voltage-gated Na(+ )channels resistant to batrachotoxin
Batrachotoxin (BTX) is a steroidal alkaloid that causes Na(+) channels to open persistently. This toxin has been used widely as a tool for studying Na(+) channel gating processes and for estimating Na(+) channel density. In this report we used point mutations to identify critical residues involved i...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19451/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9482942/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.5.2653 |
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