Control of gating mode by a single amino acid residue in transmembrane segment IS3 of the N-type Ca(2+) channel
N-type Ca(2+) channels can be inhibited by neurotransmitter-induced release of G protein βγ subunits. Two isoforms of Ca(v)2.2 α1 subunits of N-type calcium channels from rat brain (Ca(v)2.2a and Ca(v)2.2b; initially termed rbB-I and rbB-II) have different functional properties. Unmodulated Ca(v)2.2...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31898/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11296299/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.051629098 |
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