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Control of gating mode by a single amino acid residue in transmembrane segment IS3 of the N-type Ca(2+) channel

N-type Ca(2+) channels can be inhibited by neurotransmitter-induced release of G protein βγ subunits. Two isoforms of Ca(v)2.2 α1 subunits of N-type calcium channels from rat brain (Ca(v)2.2a and Ca(v)2.2b; initially termed rbB-I and rbB-II) have different functional properties. Unmodulated Ca(v)2.2...

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Bibliografische gegevens
Hoofdauteurs: Zhong, Huijun, Li, Bin, Scheuer, Todd, Catterall, William A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2001
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC31898/
https://ncbi.nlm.nih.gov/pubmed/11296299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051629098
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