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A Dimer of the Toll-Like Receptor 4 Cytoplasmic Domain Provides a Specific Scaffold for the Recruitment of Signalling Adaptor Proteins

The Toll-like receptor 4 (TLR4) is a class I transmembrane receptor expressed on the surface of immune system cells. TLR4 is activated by exposure to lipopolysaccharides derived from the outer membrane of Gram negative bacteria and forms part of the innate immune response in mammals. Like other clas...

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Bibliografski detalji
Glavni autori: Núñez Miguel, Ricardo, Wong, Joyce, Westoll, Julian F., Brooks, Heather J., O'Neill, Luke A.J., Gay, Nicholas J., Bryant, Clare E., Monie, Tom P.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1945083/
https://ncbi.nlm.nih.gov/pubmed/17726518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000788
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