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Phosphoinositide-dependent protein kinase-1 (PDK1)-independent activation of the protein kinase C substrate, protein kinase D

Phosphoinoisitide dependent kinase l (PDK1) is proposed to phosphorylate a key threonine residue within the catalytic domain of the protein kinase C (PKC) superfamily that controls the stability and catalytic competence of these kinases. Hence, in PDK1-null embryonic stem cells intracellular levels...

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Detalhes bibliográficos
Main Authors: Wood, C. David, Kelly, April P., Matthews, Sharon A., Cantrell, Doreen A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science B.V 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1942071/
https://ncbi.nlm.nih.gov/pubmed/17617409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.06.060
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