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Correlated network activity enhances synaptic efficacy via BDNF and the ERK pathway at immature CA3–CA1 connections in the hippocampus

At early developmental stages, correlated neuronal activity is thought to exert a critical control on functional and structural refinement of synaptic connections. In the hippocampus, between postnatal day 2 (P2) and P6, network-driven giant depolarizing potentials (GDPs) are generated by the synerg...

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Autori principali: Mohajerani, Majid H., Sivakumaran, Sudhir, Zacchi, Paola, Aguilera, Pedro, Cherubini, Enrico
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1941828/
https://ncbi.nlm.nih.gov/pubmed/17656555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704533104
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