Modification of adverse inflammation is required to cure new-onset type 1 diabetic hosts

In nonobese diabetic (NOD) mice with overt new-onset type 1 diabetes mellitus (T1DM), short-term treatment with a “triple-therapy” regimen [rapamycin plus agonist IL-2-related and antagonist-type, mutant IL-15-related Ig fusion proteins (IL-2.Ig and mutIL-15.Ig)] halts autoimmune destruction of insu...

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Detalhes bibliográficos
Main Authors: Koulmanda, Maria, Budo, Ejona, Bonner-Weir, Susan, Qipo, Andi, Putheti, Prabhakar, Degauque, Nicolas, Shi, Hang, Fan, Zhigang, Flier, Jeffrey S., Auchincloss, Hugh, Zheng, Xin Xiao, Strom, Terry B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1941818/
https://ncbi.nlm.nih.gov/pubmed/17670937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705863104
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