Alpha 1-antitrypsin reduces inflammation and enhances mouse pancreatic islet transplant survival

The promise of islet cell transplantation cannot be fully realized in the absence of improvements in engraftment of resilient islets. The marginal mass of islets surviving the serial peritransplant insults may lead to exhaustion and thereby contribute to an unacceptably high rate of intermediate and...

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Main Authors: Koulmanda, Maria, Bhasin, Manoj, Fan, Zhigang, Hanidziar, Dusan, Goel, Nipun, Putheti, Prabhakar, Movahedi, Babak, Libermann, Towia A., Strom, Terry B.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458386/
https://ncbi.nlm.nih.gov/pubmed/22949661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018366109
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