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Efficient repeated low-dose intravaginal infection with X4 and R5 SHIVs in rhesus macaque: Implications for HIV-1 transmission in humans
We examined the effect of inoculum dose on SHIV transmission and infection. We found that repeated low-dose intravaginal exposure with either R5-SHIV(SF162P3) or X4-SHIV(SF33A) results in infections that are blunted and rapidly controlled. Interestingly, although the transmission rate after all repe...
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Autores principales: | , , , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
2007
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1941575/ https://ncbi.nlm.nih.gov/pubmed/17258783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.12.024 |
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