Modifying Effects of the HFE Polymorphisms on the Association between Lead Burden and Cognitive Decline

BACKGROUND: As iron and lead promote oxidative damage, and hemochromatosis (HFE) gene polymorphisms increase body iron burden, HFE variant alleles may modify the lead burden and cognitive decline relationship. OBJECTIVE: Our goal was to assess the modifying effects of HFE variants on the lead burden...

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Detalhes bibliográficos
Main Authors: Wang, Florence T., Hu, Howard, Schwartz, Joel, Weuve, Jennifer, Spiro, Avron S., Sparrow, David, Nie, Huiling, Silverman, Edwin K., Weiss, Scott T., Wright, Robert O.
Formato: Artigo
Idioma:Inglês
Publicado em: National Institute of Environmental Health Sciences 2007
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1940090/
https://ncbi.nlm.nih.gov/pubmed/17687449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.9855
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