HFE H63D Polymorphism as a Modifier of the Effect of Cumulative Lead Exposure on Pulse Pressure: The Normative Aging Study

BACKGROUND: Cumulative lead exposure is associated with a widened pulse pressure (PP; the difference between systolic and diastolic blood pressure), a marker of arterial stiffness and a predictor of cardiovascular disease. Polymorphisms in the hemochromatosis gene (HFE) have been shown to modify the...

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Main Authors: Zhang, Aimin, Park, Sung Kyun, Wright, Robert O., Weisskopf, Marc G., Mukherjee, Bhramar, Nie, Huiling, Sparrow, David, Hu, Howard
Formato: Artigo
Idioma:Inglês
Publicado: National Institute of Environmental Health Sciences 2010
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944087/
https://ncbi.nlm.nih.gov/pubmed/20478760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1002251
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