Modifying roles of glutathione S-transferase polymorphisms on the association between cumulative lead exposure and cognitive function

BACKGROUND: Glutathione-S-transferase gene (GST) polymorphisms can result in variable ability of these enzymes to remove electrophilic substrates. We investigated whether the GSTP1 Val105 and GSTM1 deletion polymorphisms modify the lead-cognitive function association. METHODS: We used repeated measu...

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Detalhes bibliográficos
Main Authors: Eum, Ki-Do, Wang, Florence T., Schwartz, Joel, Hersh, Craig P., Kelsey, Karl, Wright, Robert O., Spiro, Avron, Sparrow, David, Hu, Howard, Weisskopf, Marc G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844089/
https://ncbi.nlm.nih.gov/pubmed/23958642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2013.08.002
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