Ectopic expression of N-acetylglucosaminyltransferase III in transgenic hepatocytes disrupts apolipoprotein B secretion and induces aberrant cellular morphology with lipid storage

N-Acetylglucosaminyltransferase III (GnT-III) produces “bisecting-GlcNAc” and regulates the branching of N-glycans. GnT-III activity is elevated during hepatocarcinogenesis, which is in contrast to the undetectable level found in normal hepatocytes. To determine the biological significance of GnT-II...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Ihara, Yoshito, Yoshimura, Masafumi, Miyoshi, Eiji, Nishikawa, Atsushi, Sultan, Ahmed S., Toyosawa, Satoru, Ohnishi, Akio, Suzuki, Misao, Yamamura, Ken-ichi, Ijuhin, Naokuni, Taniguchi, Naoyuki
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1998
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19400/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9482919/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.5.2526
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