Ectopic expression of N-acetylglucosaminyltransferase III in transgenic hepatocytes disrupts apolipoprotein B secretion and induces aberrant cellular morphology with lipid storage

N-Acetylglucosaminyltransferase III (GnT-III) produces “bisecting-GlcNAc” and regulates the branching of N-glycans. GnT-III activity is elevated during hepatocarcinogenesis, which is in contrast to the undetectable level found in normal hepatocytes. To determine the biological significance of GnT-II...

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Dades bibliogràfiques
Autors principals: Ihara, Yoshito, Yoshimura, Masafumi, Miyoshi, Eiji, Nishikawa, Atsushi, Sultan, Ahmed S., Toyosawa, Satoru, Ohnishi, Akio, Suzuki, Misao, Yamamura, Ken-ichi, Ijuhin, Naokuni, Taniguchi, Naoyuki
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1998
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC19400/
https://ncbi.nlm.nih.gov/pubmed/9482919
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