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Arf6 recruits the Rac GEF Kalirin to the plasma membrane facilitating Rac activation

BACKGROUND: Many studies implicate Arf6 activity in Rac-mediated membrane ruffling and cytoskeletal reorganization. Although Arf6 facilitates the trafficking of Rac1 to the plasma membrane and in many cases Arf6 activation leads to the activation of Rac1, the details of how Arf6 influences Rac funct...

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Detalhes bibliográficos
Main Authors: Koo, Tae Hyeon, Eipper, Betty A, Donaldson, Julie G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1939998/
https://ncbi.nlm.nih.gov/pubmed/17640372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-8-29
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