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The Rho-GEF Kalirin regulates bone mass and the function of osteoblasts and osteoclasts
Bone homeostasis is maintained by the balance between bone resorption by osteoclasts and bone formation by osteoblasts. Dysregulation in the activity of the bone cells can lead to osteoporosis, a disease characterized by low bone mass and an increase in bone fragility and risk of fracture. Kalirin i...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3934571/ https://ncbi.nlm.nih.gov/pubmed/24380811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2013.12.023 |
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