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The Rho-GEF Kalirin regulates bone mass and the function of osteoblasts and osteoclasts

Bone homeostasis is maintained by the balance between bone resorption by osteoclasts and bone formation by osteoblasts. Dysregulation in the activity of the bone cells can lead to osteoporosis, a disease characterized by low bone mass and an increase in bone fragility and risk of fracture. Kalirin i...

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Bibliografske podrobnosti
Main Authors: Huang, Su, Eleniste, Pierre P., Wayakanon, Kornchanok, Mandela, Prashant, Eipper, Betty A., Mains, Richard E., Allen, Matthew R., Bruzzaniti, Angela
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934571/
https://ncbi.nlm.nih.gov/pubmed/24380811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2013.12.023
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