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Multiple prethymic defects underlie age-related loss of T progenitor competence
Aging in mice and humans is characterized by declining T-lymphocyte production in the thymus, yet it is unclear whether aging impacts the T-lineage potential of hematopoietic progenitors. Although alterations in the lymphoid progenitor content of aged mouse bone marrow (BM) have been described, irra...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1939899/ https://ncbi.nlm.nih.gov/pubmed/17456721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-01-071605 |
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