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Multiple prethymic defects underlie age-related loss of T progenitor competence

Aging in mice and humans is characterized by declining T-lymphocyte production in the thymus, yet it is unclear whether aging impacts the T-lineage potential of hematopoietic progenitors. Although alterations in the lymphoid progenitor content of aged mouse bone marrow (BM) have been described, irra...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zediak, Valerie P., Maillard, Ivan, Bhandoola, Avinash
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1939899/
https://ncbi.nlm.nih.gov/pubmed/17456721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-01-071605
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