Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: applications in diagnostic imaging and therapy

BACKGROUND: Resistance to modern adjuvant treatment is in part due to the failure of programmed cell death. Therefore the molecules that execute the apoptotic program are potential targets for the development of anti-cancer therapeutics. The sigma-2 receptor has been found to be over-expressed in so...

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Main Authors: Kashiwagi, Hiroyuki, McDunn, Jonathan E, Simon, Peter O, Goedegebuure, Peter S, Xu, Jinbin, Jones, Lynne, Chang, Katherine, Johnston, Fabian, Trinkaus, Kathryn, Hotchkiss, Richard S, Mach, Robert H, Hawkins, William G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1939854/
https://ncbi.nlm.nih.gov/pubmed/17631687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-6-48
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