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Secretion of LamB-LacZ by the Signal Recognition Particle Pathway of Escherichia coli

LamB-LacZ fusion proteins have classically been used in studies of the general secretion pathway of Escherichia coli. Here we describe how increasing signal sequence hydrophobicity routes LamB-LacZ Hyb42-1 to the signal recognition particle (SRP) pathway. Secretion of this hydrophobic fusion variant...

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Bibliografiske detaljer
Main Authors: Bowers, Christina Wilson, Lau, Fion, Silhavy, Thomas J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC193965/
https://ncbi.nlm.nih.gov/pubmed/13129940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.19.5697-5705.2003
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