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Defective Brain Development in Mice Lacking the Hif-1α Gene in Neural Cells

Hypoxia-inducible factor 1α (HIF-1α) is essential for vascular development during embryogenesis and pathogenesis. However, little is known about its role in brain development. To investigate the function of HIF-1α in the central nervous system, a conditional knockout mouse was made with the Cre/LoxP...

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Publicado no:Mol Cell Biol
Principais autores: Tomita, Shuhei, Ueno, Masaki, Sakamoto, Masami, Kitahama, Yuki, Ueki, Masaaki, Maekawa, Nobuhiro, Sakamoto, Haruhiko, Gassmann, Max, Kageyama, Ryoichiro, Ueda, Natsuo, Gonzalez, Frank J., Takahama, Yousuke
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2003
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC193947/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12972594/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.19.6739-6749.2003
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