Validation of Serological Correlate of Protection for Meningococcal C Conjugate Vaccine by Using Efficacy Estimates from Postlicensure Surveillance in England

Meningococcal C conjugate (MCC) vaccines were licensed on the basis of serological correlates of protection without efficacy data. The original correlate of protection was established by using a serum bactericidal antibody assay (SBA) with human complement (hSBA), with titers ≥4 predicting protectio...

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Detalhes bibliográficos

Publicado no:	Clin Diagn Lab Immunol
Principais autores:	Andrews, Nick, Borrow, Ray, Miller, Elizabeth
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Experimental Clinical Investigation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC193909/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12965904/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/CDLI.10.5.780-786.2003
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