Effects of Prior Polysaccharide Vaccination on Magnitude, Duration, and Quality of Immune Responses to and Safety Profile of a Meningococcal Serogroup C Tetanus Toxoid Conjugate Vaccination in Adults

Extensive use of meningococcal AC polysaccharide (MACP) vaccines has raised concerns about induction of immunologic hyporesponsiveness to C polysaccharide. We investigated the immunogenicity and safety of a meningococcal C-tetanus conjugate (MCC-TT) vaccine in naïve adults and prior MACP vaccinees....

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Main Authors: Southern, Jo, Deane, Sarah, Ashton, Lindsey, Borrow, Ray, Goldblatt, David, Andrews, Nick, Balmer, Paul, Morris, Rhonwen, Kroll, J. Simon, Miller, Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
Assuntos:
Antibodies and Mediators of Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC524764/
https://ncbi.nlm.nih.gov/pubmed/15539513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.11.6.1100-1104.2004
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