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Phage escape libraries for checkmate analysis
Ligand-binding epitopes of proteins can mutate rapidly, as shown by viral mutations that lead to escape from neutralizing antibodies. We have undertaken to recreate in vitro the evolutionary competition between viral mutations that allow escape from antibody binding and host mutations that generate...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1937530/ https://ncbi.nlm.nih.gov/pubmed/17646645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705362104 |
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