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Crystal structure of the GINS complex and functional insights into its role in DNA replication
The GINS complex, which contains the four subunits Sld5, Psf1, Psf2, and Psf3, is essential for both the initiation and progression of DNA replication in eukaryotes. GINS associates with the MCM2-7 complex and Cdc45 to activate the eukaryotic minichromosome maintenance helicase. It also appears to i...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1937527/ https://ncbi.nlm.nih.gov/pubmed/17652513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705558104 |
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