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Selective Degradation of AU-Rich mRNAs Promoted by the p37 AUF1 Protein Isoform
An AU-rich element (ARE) consisting of repeated canonical AUUUA motifs confers rapid degradation to many cytokine mRNAs when present in the 3′ untranslated region. Destabilization of mRNAs with AREs (ARE-mRNAs) is consistent with the interaction of ARE-binding proteins such as tristetraprolin and th...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2003
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC193711/ https://ncbi.nlm.nih.gov/pubmed/12944492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.18.6685-6693.2003 |
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