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A method to assess compositional bias in biological sequences and its application to prion-like glutamine/asparagine-rich domains in eukaryotic proteomes

We have derived a novel method to assess compositional biases in biological sequences, which is based on finding the lowest-probability subsequences for a given residue-type set. As a case study, the distribution of prion-like glutamine/asparagine-rich ((Q+N)-rich) domains (which are linked to amylo...

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Bibliografische Detailangaben
Veröffentlicht in:Genome Biol
Hauptverfasser: Harrison, Paul M, Gerstein, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2003
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC193619/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12801414/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/gb-2003-4-6-r40
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