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Evidence for a transcriptional activation function of BRCA1 C-terminal region

Mutations in BRCA1 account for 45% of families with high incidence of breast cancer and for 80–90% of families with both breast and ovarian cancer. BRCA1 protein includes an amino-terminal zinc finger motif as well as an excess of negatively charged amino acids near the C terminus. In addition, BRCA...

詳細記述

保存先:
書誌詳細
主要な著者: Monteiro, Alvaro N. A., August, Avery, Hanafusa, Hidesaburo
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences of the USA 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC19361/
https://ncbi.nlm.nih.gov/pubmed/8942979
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