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Evidence for a transcriptional activation function of BRCA1 C-terminal region
Mutations in BRCA1 account for 45% of families with high incidence of breast cancer and for 80–90% of families with both breast and ovarian cancer. BRCA1 protein includes an amino-terminal zinc finger motif as well as an excess of negatively charged amino acids near the C terminus. In addition, BRCA...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The National Academy of Sciences of the USA
1996
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC19361/ https://ncbi.nlm.nih.gov/pubmed/8942979 |
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