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Targeted disruption of GPR7, the endogenous receptor for neuropeptides B and W, leads to metabolic defects and adult-onset obesity
Gold-thioglucose (GTG) induces lesions in the ventromedial nucleus of the hypothalamus, resulting in hyperphagia and obesity. To identify genes involved in the hypothalamic regulation of energy homeostasis, we used a screen for genes that are dysregulated in GTG-induced obese mice. We found that GPR...
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Main Authors: | , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
National Academy of Sciences
2003
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC193597/ https://ncbi.nlm.nih.gov/pubmed/12925742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1334189100 |
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