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Targeted disruption of GPR7, the endogenous receptor for neuropeptides B and W, leads to metabolic defects and adult-onset obesity

Gold-thioglucose (GTG) induces lesions in the ventromedial nucleus of the hypothalamus, resulting in hyperphagia and obesity. To identify genes involved in the hypothalamic regulation of energy homeostasis, we used a screen for genes that are dysregulated in GTG-induced obese mice. We found that GPR...

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Sonraí Bibleagrafaíochta
Main Authors: Ishii, Makoto, Fei, Hong, Friedman, Jeffrey M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2003
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC193597/
https://ncbi.nlm.nih.gov/pubmed/12925742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1334189100
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