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Mapping of an Origin of DNA Replication in the Promoter of Fragile X Gene FMR1

An origin of bidirectional DNA replication was mapped to the promoter of the FMR1 gene in human chromosome Xq27.3, which has been linked to the fragile X syndrome. This origin is adjacent to a CpG island and overlaps the site of expansion of the triplet repeat (CGG) at the fragile X instability site...

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Detalhes bibliográficos
Main Authors: Brylawski, Bruna P., Chastain, Paul D., Cohen, Stephanie M., Cordeiro-Stone, Marila, Kaufman, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934615/
https://ncbi.nlm.nih.gov/pubmed/17196195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2006.10.004
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