An Origin of DNA Replication in the Promoter Region of the Human Fragile X Mental Retardation (FMR1) Gene

Fragile X syndrome, the most common form of inherited mental retardation in males, arises when the normally stable 5 to 50 CGG repeats in the 5′ untranslated region of the fragile X mental retardation protein 1 (FMR1) gene expand to over 200, leading to DNA methylation and silencing of the FMR1 prom...

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Bibliographic Details
Main Authors: Gray, Steven J., Gerhardt, Jeannine, Doerfler, Walter, Small, Lawrence E., Fanning, Ellen
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800797/
https://ncbi.nlm.nih.gov/pubmed/17101793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01382-06
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