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Foxo3 is required for the regulation of oxidative stress in erythropoiesis
Erythroid cells accumulate hemoglobin as they mature and as a result are highly prone to oxidative damage. However, mechanisms of transcriptional control of antioxidant defense in erythroid cells have thus far been poorly characterized. We observed that animals deficient in the forkhead box O3 (Foxo...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1934587/ https://ncbi.nlm.nih.gov/pubmed/17671650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31807 |
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