Foxo3 is required for the regulation of oxidative stress in erythropoiesis

Erythroid cells accumulate hemoglobin as they mature and as a result are highly prone to oxidative damage. However, mechanisms of transcriptional control of antioxidant defense in erythroid cells have thus far been poorly characterized. We observed that animals deficient in the forkhead box O3 (Foxo...

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Detaylı Bibliyografya
Asıl Yazarlar: Marinkovic, Dragan, Zhang, Xin, Yalcin, Safak, Luciano, Julia P., Brugnara, Carlo, Huber, Tara, Ghaffari, Saghi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2007
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934587/
https://ncbi.nlm.nih.gov/pubmed/17671650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31807
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